Table 3

Performance evaluation for Alzheimer’s disease
Selection Rank Recall Precision F-score
Baseline: Genes / Proteins 60 0.10 0.92 0.17
230 0.30 0.73 0.42
469 0.50 0.61 0.55
Maximal F-score 728 0.67 0.52 0.59
Baseline + Clinical Management 61 0.10 0.90 0.17
226 0.30 0.75 0.42
465 0.50 0.61 0.55
Maximal F-score 682 0.65 0.54 0.59
Baseline + Evidence Marker 62 0.10 0.89 0.17
225 0.30 0.75 0.42
464 0.50 0.61 0.55
Maximal F-score 654 0.62 0.54 0.57
Baseline +Prognosis 63 0.10 0.87 0.17
247 0.30 0.68 0.41
541 0.50 0.52 0.51
Maximal F-score 740 0.61 0.47 0.53
Baseline + Diagnostics 64 0.10 0.86 0.17
237 0.30 0.71 0.42
494 0.50 0.57 0.53
Maximal F-score 520 0.52 0.57 0.54
Baseline + Statistics 64 0.10 0.86 0.17
227 0.30 0.74 0.42
678 0.50 0.42 0.45
Maximal F-score 377 0.41 0.62 0.49
Baseline + Clinical Management + Evidence Marker 60 0.10 0.92 0.17
224 0.30 0.75 0.42
451 0.50 0.63 0.56
Maximal F-score 555 0.57 0.59 0.58
Baseline + Clinical Management + Evidence Marker + Prognosis 61 0.10 0.90 0.17
230 0.30 0.73 0.42
568 0.50 0.50 0.50
Maximal F-score 479 0.47 0.56 0.51

Genes were ranked based on frequency and evaluated against the Alzheimer’s gold standard. For the different selections recall, precision, F-score and rank has been estimated for 10, 30, and 50% recall. In addition the maximal recall has been estimated.

Younesi et al.

Younesi et al. BMC Medical Informatics and Decision Making 2012 12:148   doi:10.1186/1472-6947-12-148

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