Table 4

Pharmacokinetic Geometric Mean ratios of AVI-014/Filgrastim at 8 μg/kg

PK parameter

Dose μg/kg

Geometric Mean AVI-014 (n = 8)

Geometric Mean Filgrastin (n = 8)

P value

Geometric Mean Ratio (90% CI)


AUC(0–72)

8

301,979

340,837

0.3669

0.89 (0.69, 1.14)


Cmax

8

30,467

40,325

0.0550

0.76 (0.58, 0.98)


Varki et al. BMC Clinical Pharmacology 2009 9:2   doi:10.1186/1472-6904-9-2

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