Table 3

Comparison of change in average urine excretion compared to baseline for participants who completed six rounds of phase 2 (n = 20).

Element

Baseline (mcg/g- creatinine)

Change after 1st dose

Change after 9th dose

Change after round 2

Change after round 4

Change after round 6


Pb

0.64

935%***

1562%***

1001%***

1063%***

1005%***

Sn

3.5

118%*

269%

205%

213%

115%

Bi

0.06

312%

296%

787%

261%

11%

U

0.014

29%

79%

-32%

-11%

282%+

Hg

0.85

120%*

37%

98%***

70%

59%+

Tl

0.16

54%**

44%*

13%

18%

28%

Sb

0.10

67%+

26%

9%

23%

27%

W

0.41

36%+

-11%

14%

52%

25%

Al

8.3

125%

1%

26%

38%

-12%

Ni

5.8

-2%

25%

36%+

68%*

25%

Cd

0.35

14%

-32%*

-7%

0%

-17%

As

31

4%

-13%

-39%***

-42%***

-31%+


+ P < 0.1

*P < 0.05

** P < 0.01

*** P < 0.001

Significant results are highlighted in bold font.

Adams et al. BMC Clinical Pharmacology 2009 9:16   doi:10.1186/1472-6904-9-16

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