Table 1

Ethic committee approvals

Study
Ethical Committee

- single-dose, comparing 1 and 2 mg lozenges with 2 mg gum
- multiple-dose, comparing 1 mg lozenge with 2 mg gum
CCPPRB de Franche-Comté, France
- multiple-dose, comparing 1 and 2 mg lozenges with 4 mg gum
CCPPRB of the Hôtel-Dieu Hospital (Lyon – France)
- safety assessment of 1 mg lozenge after swallowing
CREC Regipharm (Brussels – Belgium)
- French efficacy trial
CCPPRB of the Pitié-Salpêtrière Hospital (Paris – France)
- US efficacy trial
IRB at Research Testing Laboratories, Inc. (Great Neck, NY, USA)

Dautzenberg et al. BMC Clinical Pharmacology 2007 7:11   doi:10.1186/1472-6904-7-11