Figure 9.

Comparison of acetone PBPK model arterial (red line) and antecubital vein (blue line) concentrations with the experimental data (squares) of Wigaeus et. al. [15] (top panel). The bottom panel compares the model antecubital vein/arterial concentration ratio (red line) versus the experimental values (squares). Using a fractional contribution of muscle to antecubital vein blood of 0.5.