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BMC Clinical Pharmacology

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Editor-in-Chief
Melissa Norton, MD

Medical Editor
Jigisha Patel, MRCP PhD

In-house Editor
Matthew Kaiser PhD


Welcome to BMC Clinical Pharmacology published by BioMed Central
BMC Clinical Pharmacology is an open access journal publishing original peer-reviewed research articles in all aspects of clinical pharmacology. BMC Clinical Pharmacology (ISSN 1472-6904) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus and Google Scholar.



BMC Featured articles

Levitt, 2010
BMC Clinical Pharmacology 2010, 10:1
The limited diffusion of highly fat soluble persistent organic chemicals between adipose tissue and blood can be explained because as the blood/water partition coefficient increases the adipose perfusion rate decreases.
Image: CLCsPics on Flickr, Creative Commons Attrib-SA 2 Generic
BMC Clinical Pharmacology 2009, 9:19
The time to maximum blood concentration of ibuprofen is cut from 90 minutes to just 35 minutes if ibuprofen sodium dihydrate is taken rather than the standard formulation, but adding poloxamer makes no significant difference to bioavailability.
Credit Nephron
BMC Clinical Pharmacology 2009, 9:18
Recombinant and high-density lipoprotein complexed forms of serum paraoxonase are stable, do not cause toxic effects and show efficacy against organophosphate poisoning in mice, so have the potential to treat organophosphate toxicity and atherosclerosis in humans.


BMC  Latest articles published in BMC Clinical Pharmacology        [more info]


Research article
Comparative in vitro study of the antimicrobial activities of different commercial antibiotic products for intravenous administration
Edelberto Silva, Jorge A Diaz, Maria J Arias, Angela P Hernandez, Andres de la Torre
BMC Clinical Pharmacology 2010, 10:3 (29January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Reporting randomised clinical trials of analgesics after traumatic or orthopaedic surgery is inadequate: a systematic review
Eva Montane, Antoni Vallano, Xavier Vidal, Cristina Aguilera, Joan-Ramon Laporte
BMC Clinical Pharmacology 2010, 10:2 (12January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Quantitative relationship between the octanol/water partition coefficient and the diffusion limitation of the exchange between adipose and blood
David G Levitt
BMC Clinical Pharmacology 2010, 10:1 (7January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers
Peter M Dewland, Sandie Reader, Phillip Berry
BMC Clinical Pharmacology 2009, 9:19 (4December2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes
Leonid Gaidukov, Dganit Bar, Shiri Yacobson, Esmira Naftali, Olga Kaufman, Rinat Tabakman, Dan S Tawfik, Etgar Levy-Nissenbaum
BMC Clinical Pharmacology 2009, 9:18 (17November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part B - Behavioral results
James B Adams, Matthew Baral, Elizabeth Geis, Jessica Mitchell, Julie Ingram, Andrea Hensley, Irene Zappia, Sanford Newmark, Eva Gehn, Robert A Rubin, Ken Mitchell, Jeff Bradstreet, Jane El-Dahr
BMC Clinical Pharmacology 2009, 9:17 (23October2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A - Medical results
James B Adams, Matthew Baral, Elizabeth Geis, Jessica Mitchell, Julie Ingram, Andrea Hensley, Irene Zappia, Sanford Newmark, Eva Gehn, Robert A Rubin, Ken Mitchell, Jeff Bradstreet, Jane El-Dahr
BMC Clinical Pharmacology 2009, 9:16 (23October2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
Evaluation of risk factor management of patients treated on an internal nephrology ward: a pilot study
Gunar Stemer, Sonja Zehetmayer, Rosa Lemmens-Gruber
BMC Clinical Pharmacology 2009, 9:15 (6September2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria
Kazeem A Oshikoya, Jacob O Awobusuyi
BMC Clinical Pharmacology 2009, 9:14 (11August2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A Phase 1 Trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion
Debra S Harris, Thomas Everhart, Peyton Jacob III, Emil Lin, John E Mendelson, Reese T Jones
BMC Clinical Pharmacology 2009, 9:13 (1August2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
Demographic determinants and effect of pre-operative angiotensin converting enzyme inhibitors and angiotensin receptor blockers on the occurrence of atrial fibrillation after CABG surgery.
Nasir Shariff, Steven Zelenkofske, Sherrine Eid, Michael J Weiss, Muneeruddin Q Mohammed
BMC Cardiovascular Disorders 2010, 10:7 (8February2010)
[Abstract] [Provisional PDF]

Research article
Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes
Laura Ceballos, Laura Moreno, Luis Alvarez, Laura Shaw, Ian Fairweather, Carlos Lanusse
BMC Veterinary Research 2010, 6:8 (3February2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Follow-up of phase I trial of adalimumab and rosiglitazone in FSGS: III. Report of the FONT study group
Alexandra Peyser, Nathaniel MacHardy, Freya Tarapore, Jacqueline MacHardy, Leslie Powell, Debbie S Gipson, Virginia Savin, Cynthia Pan, Teresa Kump, Suzanne Vento, Howard Trachtman
BMC Nephrology 2010, 11:2 (29January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Duration of clopidogrel treatment and risk of mortality and recurrent myocardial infarction among 11 680 patients with myocardial infarction treated with percutaneous coronary intervention: a cohort study
Rikke Sorensen, Steen Z Abildstrom, Peter Weeke, Emil L Fosbol, Fredrik Folke, Morten L Hansen, Peter R Hansen, Jan K Madsen, Ulrik Abildgaard, Lars Kober, Henrik E Poulsen, Christian Torp-Pedersen, Gunnar H Gislason
BMC Cardiovascular Disorders 2010, 10:6 (29January2010)
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Research article
Chordoma: clinical characteristics, management and prognosis of a case series of 25 patients.
Virginia Ferraresi, Carmen Nuzzo, Carmine Zoccali, Ferdinando Marandino, Antonello Vidiri, Nicola Salducca, Massimo Zeuli, Diana Giannarelli, Francesco Cognetti, Roberto Biagini
BMC Cancer 2010, 10:22 (28January2010)
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Research article
Applying diagnosis and pharmacy-based risk models to predict pharmacy use in Aragon, Spain: The impact of a local calibration.
Amaia Calderon-Larranaga, Chad Abrams, Beatriz Poblador-Plou, Jonathan P Weiner, Alexandra Prados-Torres
BMC Health Services Research 2010, 10:22 (21January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Review
The multiple functions of the endocannabinoid system: a focus on the regulation of food intake.
Eduardo Tibirica
Diabetology & Metabolic Syndrome 2010, 2:5 (21January2010)
[Abstract] [Provisional PDF]

Case report
Allergic reaction related to ramipril use: a case report
Renata C Alencar, Roberta A Cobas, Marilia B Gomes
Diabetology & Metabolic Syndrome 2010, 2:4 (20January2010)
[Abstract] [Provisional PDF]

Case report
Sigma-1 receptor agonist fluvoxamine for delirium in patients with Alzheimer's disease
Tsutomu Furuse, Kenji Hashimoto
Annals of General Psychiatry 2010, 9:6 (20January2010)
[Abstract] [Full Text] [PDF]

Research article
Design, recruitment, and retention of African-American smokers in a pharmacokinetic study
Babalola Faseru, Lisa S Cox, Carrie A Bronars, Isaac Opole, Gregory A Reed, Matthew S Mayo, Jasjit S Ahluwalia, Kolawole S Okuyemi
BMC Medical Research Methodology 2010, 10:6 (19January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

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