Table 1 |
|||
|
Summary of KRAS mutations identified. |
|||
|
KRAS mutation |
Amino acid change |
*Number (%) mutations |
Distribution colon/rectum |
|
|
|||
|
c.35G>A |
p.Gly12 Asp |
19 (33) |
13/6 |
|
c.38G>A |
p.Gly13Asp |
12 (21) |
8/5 |
|
c.35G>T |
p.Gly12Val |
10 (18) |
4/6 |
|
c.34G>T |
p.Gly12Cys |
7 (12) |
6/1 |
|
c.34G>A |
p.Gly12Ser |
5 (9) |
1/4 |
|
c.35G>C |
p.Gly12Ala |
4 (7) |
3/1 |
|
c.34G>C |
p.Gly12Arg |
- |
- |
|
|
|||
|
*Represents 53 tumors, including 3 with coexisting mutations |
|||
|
Jönsson et al. BMC Clinical Pathology 2009 9:8 doi:10.1186/1472-6890-9-8 |
|||