Open Access Research article

Improved Methodology for Assessment of mRNA Levels in Blood of Patients with FMR1 Related Disorders

David E Godler1*, Danuta Z Loesch12, Richard Huggins3, Lavinia Gordon4, Howard R Slater56, Freya Gehling1, Trent Burgess5 and KH Andy Choo16

Author Affiliations

1 Chromosome and Chromatin Research, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia

2 School of Psychological Science, La Trobe University, Melbourne, Australia

3 Department of Mathematics and Statistics, University of Melbourne, Melbourne, Australia

4 The Bioinformatics Unit, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia

5 VCGS Cytogenetics Laboratory, Murdoch Research Institute, Royal Children's Hospital, Melbourne, Australia

6 Department of Pediatrics, University of Melbourne, Melbourne, Australia

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BMC Clinical Pathology 2009, 9:5  doi:10.1186/1472-6890-9-5

Published: 9 June 2009

Additional files

Additional file 1:

FMR1ex3.4 and FMR1ex13.14 assays detect transcripts of a similar abundance in peripheral blood of patients (n = 54) with small to intermediate size expansions in RNA samples of high total RNA quality.

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