Liver, patient 1, cytochrome oxidase stain. 6a: low power view of cryostat section; islet of stained cells surrounded by unstained parenchyma. Large dark granules are erythrocytes in sinusoids and Kupffer cells that stain for peroxidase (arrow). Patient 1. 6b: high power of sharp border between COX stained and unstained parenchymal cells. Numerous tightly packed granules are mitochondria. In the unstained cells, the fewer small round granules are peroxisomes reacting by their catalase. Postosmicated, semithin plastic section.
Roels et al. BMC Clinical Pathology 2009 9:4 doi:10.1186/1472-6890-9-4