Table 3

Change in amino acid concentrations in whole blood after 24 hours at room temperature and on ice.

% Change at 24 h at RTa, b

% Change at 24 h on iceb


Group 1 - ≤ 10% change at RTa over 24 h


Citrulline

-4 (-6, 4)

-7 (-9, -4)


Glutamine

-10 (-13, -10)

-5 (-5, -4)


Hydroxyproline

8 (7,9)

-3 (-4,-3)


Methionine

0 (-2, 1)

1 (1, 6)


Tryptophan

7 (5, 8)

4 (4, 6)


Tyrosine

8 (5, 12)

-2 (-3, -1)


Valine

8 (4, 11)

1 (0, 1)


Group 2 - > 10% increase at RTa over 24 h


Alanine

18 (16,20)

0 (-1, 0)


Asparagine

17 (12, 21)

0 (-1, +3)


Glutamate

593 (563, 612)

38 (92, 186)


Glycine

26 (24, 34)

3 (2, 4)


Histidine

23 (17, 27)

1 (0, 1)


Isoleucine

16 (10, 21)

0 (-1, 2)


Leucine

23 (17, 34)

2 (1, 5)


Lysine

19 (18, 19)

2 (1, 5)


Ornithine

183 (180, 224)

24 (23,25)


Phenylalanine

15 (14,22)

1 (1, 3)


Proline

11 (6,13)

1 (-1,2)


Serine

18 (17,28)

6 (2,6)


Taurine

100 (94, 102)

126 (120, 147)


Threonine

11 (10, 14)

-2 (-5, 0)


Group 3 - > 10% decrease at RTa over 24 h


Arginine

-43 (-65, -43)

-1 (-5, 4)


a. RT - Room temperature

b. Expressed as median % change (Interquartile range)

Note - % change values are an increase (positive change) unless otherwise specified.

Davis et al. BMC Clinical Pathology 2009 9:10   doi:10.1186/1472-6890-9-10

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