Table 3 |
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Change in amino acid concentrations in whole blood after 24 hours at room temperature and on ice. |
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% Change at 24 h at RTa, b |
% Change at 24 h on iceb |
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Group 1 - ≤ 10% change at RTa over 24 h |
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Citrulline |
-4 (-6, 4) |
-7 (-9, -4) |
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Glutamine |
-10 (-13, -10) |
-5 (-5, -4) |
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Hydroxyproline |
8 (7,9) |
-3 (-4,-3) |
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Methionine |
0 (-2, 1) |
1 (1, 6) |
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Tryptophan |
7 (5, 8) |
4 (4, 6) |
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Tyrosine |
8 (5, 12) |
-2 (-3, -1) |
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Valine |
8 (4, 11) |
1 (0, 1) |
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Group 2 - > 10% increase at RTa over 24 h |
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Alanine |
18 (16,20) |
0 (-1, 0) |
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Asparagine |
17 (12, 21) |
0 (-1, +3) |
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Glutamate |
593 (563, 612) |
38 (92, 186) |
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Glycine |
26 (24, 34) |
3 (2, 4) |
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Histidine |
23 (17, 27) |
1 (0, 1) |
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Isoleucine |
16 (10, 21) |
0 (-1, 2) |
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Leucine |
23 (17, 34) |
2 (1, 5) |
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Lysine |
19 (18, 19) |
2 (1, 5) |
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Ornithine |
183 (180, 224) |
24 (23,25) |
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Phenylalanine |
15 (14,22) |
1 (1, 3) |
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Proline |
11 (6,13) |
1 (-1,2) |
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Serine |
18 (17,28) |
6 (2,6) |
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Taurine |
100 (94, 102) |
126 (120, 147) |
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Threonine |
11 (10, 14) |
-2 (-5, 0) |
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Group 3 - > 10% decrease at RTa over 24 h |
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Arginine |
-43 (-65, -43) |
-1 (-5, 4) |
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a. RT - Room temperature b. Expressed as median % change (Interquartile range) Note - % change values are an increase (positive change) unless otherwise specified. |
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Davis et al. BMC Clinical Pathology 2009 9:10 doi:10.1186/1472-6890-9-10 |
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