Table 1

Clinicopathologic features of invasive squamous cell carcinoma cases in relation to different studied markers.

Clinical features

No. = 43

Cyclin D1

n = 18

Cyclin E

n = 38

Cdk-4

n = 40

P27 KIp1

n = 37

P53

n = 19

mdm2

n = 22

P21 waf

n = 29

Rb

n = 30

P16

n = 40

Ki-67

n = 36


Tumor size

<4 cm

15

2

10

12

9

2

4

7

13

13

10

4 cm

28

16

28

28

28

17

18

22

27

17

26

(p = 0.003)

(p = 0.003)

p = 0.047

p = 0.003

p = 0.003

(p = 0.001)

(p = 0.008)

Tumor type

LK-SCC

13

7

9

13

7

1

3

10

12

2

8

LNK-SCC

26

10

25

24

26

15

16

17

24

24

24

SmCC

4

1

4

3

4

3

3

2

3

4

4

p = 0.047

p = 0.01

p = 0.01

Stromal invasion

<1/2

15

6

13

15

12

7

7

9

9

14

12

1/2

28

12

25

25

25

12

15

20

21

26

24

p = 0.024

p = 0.037

Lymph nodes

Positive

13

5

9

11

7

2

4

10

7

11

7

Negative

30

13

29

29

30

17

18

19

23

29

29

p = 0.001

p = 0.001

Lympho- vascular

Positive

7

5

5

5

4

2

2

5

4

5

6

Negative

36

13

33

35

33

17

20

24

26

35

30

p = 0.035

p = 0.003

p = 0.001

Vaginal involvement

Positive

12

6

10

10

7

5

3

8

9

10

11

Negative

31

12

28

30

30

14

19

21

21

30

25

(p = 0.037)

FIGO Stage

I&II

17

3

15

16

12

2

9

12

13

17

10

III&IV

26

15

23

24

25

17

13

17

17

23

26

(p = 0.008)

p = 0.002

p = 0.003

p = 0.019


* LNK-SCC: Large non-keratinized squamous cell carcinoma LNK-SCC: Large keratinized squamous cell carcinoma SmCC: Small cell carcinoma

Bahnassy et al. BMC Clinical Pathology 2007 7:4   doi:10.1186/1472-6890-7-4

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