Table 4

Unstimulated (UPS) and stimulated (SPS) parotid salivary flow rates, composition including pH, PCO2, buffer capacity, degree of saturation with regard to hydroxyapatite, and critical pH in the patients with primary Sjögren's syndrome (pSS, (n = 20)) and the healthy controls (n = 20). Results are given in medians (range).

UPS

SPS


pSS

Healthy controls

P-value

pSS

Healthy controls

P-value


Flow rate (ml/min/gland)

0.00* (0.00–0.04) (n = 20)

0.04 (0.00–0.13) (n = 20)

<0.001

0.10 (0.00–0.87) (n = 20)

0.72 (0.17–1.57) (n = 20)

<0.001

pH

5.5 (4.9–6.2) (n = 7)

6.1 (5.4–6.6) (n = 14)

0.008

6.8 (5.3–7.6) (n = 13)

7.1 (6.8–8.0) (n = 19)

0.020

PCO2 (KPa)

2.5 (2.1–4.8) (n = 7)

3.3 (0.5–7.9) (n = 14)

0.455

3.5 (1.4–7.5) (n = 13)

5.5 (0.3–10.0) (n = 19)

0.021

Na+ (mM)

7.0 (0.0–111.0) (n = 9)

0.0 (0.0–8.5) (n = 19)

0.002

15.5 (3.5–93.0) (n = 15)

7.5 (0.0–65.0) (n = 20)

0.034

K+ (mM)

24.5 (4.5–52.5) (n = 9)

29.0 (17.5–62.0) (n = 19)

0.209

26.5 (12.0–53.0) (n = 15)

23.0 (18.0–40.0) (n = 20)

0.689

Total calcium (mM)

1.0 (0.4–2.4) (n = 9)

1.0 (0.6–4.1) (n = 16)

0.887

1.1 (0.6–1.8) (n = 13)

0.8 (0.4–1.4) (n = 20)

0.008

Cl- (mM)

22.5 (5.0–100.5) (n = 9)

19.0 (12.0–43.0) (n = 19)

0.588

27.0 (12.5–94.0) (n = 14)

15.5 (9.0–59.0) (n = 20)

0.037

Bicarbonate (mM)

0.2 (0.0–0.8) (n = 8)

0.8 (0.1–3.5) (n = 14)

0.017

3.6 (0.1–26.8) (n = 12)

11.3 (3.8–43.9) (n = 19)

0.025

Total phosphate (mM)

5.6 (2.3–15.0) (n = 7)

9.3 (4.1–18.9) (n = 16)

0.066

6.1 (2.1–8.2) (n = 11)

5.2 (3.2–16.9) (n = 20)

0.577

Total protein (mg/ml)

1.11 (0.47–8.97) (n = 9)

2.02 (0.64–5.34) (n = 18)

0.316

1.33 (0.62–6.66) (n = 14)

1.60 (0.84–4.19) (n = 20)

0.589

Total protein output (mg/min)

0 (0–0.18) (n = 9)

0.07 (0–0.30) (n = 18)

<0.001

0.13 (0–1.38) (n = 14)

1.30 (0.29–5.42) (n = 20)

<0.001

Amylase activity (μkat/l)

7760 (3700–21200)

(n = 7)

5815 (1670–27140)

(n = 18)

0.193

5220 (560–17240)

(n = 13)

5520 (710–14710)

(n = 20)

0.624

β(mmol H+/l. pH unit)

1.2 (0.1–2.9) (n = 7)

4.0 (2.3–8.9) (n = 13)

<0.001

4.4 (0.5–6.7) (n = 10)

5.2 (0.7–10.1) (n = 19)

0.171

DSHAP

1.4 (0.2–3.6) (n = 9)

3.1 (2.5–10.4) (n = 16)

0.001

7.3 (0.6–21.4) (n = 13)

10.0 (4.5–22.0) (n = 19)

0.372

Critical pH

5.4 (5.1–6.2) (n = 7)

5.3 (5.0–5.5) (n = 16)

0.413

5.5 (5.2–6.2) (n = 11)

5.7 (5.2–5.8) (n = 19)

0.611


The buffer capacity (β) was calculated from the bicarbonate and phosphate concentrations individually for each saliva sample at its pH value, DSHAP denotes the degree of saturation with regard to hydroxyapatite. P-value obtained by a Wilcoxon's rank sum test. * corresponds to mean value below 0.01 ml/min.

Pedersen et al. BMC Clinical Pathology 2005 5:4   doi:10.1186/1472-6890-5-4

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