Table 1

Anamnestic data and results of self-assessed oral dryness of the female patients with primary Sjögren's syndrome (pSS) and the female healthy controls. Results are given as number of patients or scores (yes/no) and as means ± SD.

pSS (n = 20)

Healthy controls (n = 20)

P-value


Age (years)

60 ± 15

56 ± 13

0.437a

Duration of disease (years)*

6 ± 7

0

NA

Duration of symptoms (years)

10 ± 7

0

NA

Xerogenic medicines (yes/no)

7/13

0/20

NA

Smokers (yes/no)§

5/15

0/20

NA

Cigarettes per day (smokers only)§

7 (2–20)

0

NA

Tooth brushing (times per day)

3 ± 1

2 ± 1

0.001a

Dental floss and/or toothpicks daily (yes/no)

16/4

15/5

1.000b

Dental visits per year (number)

3 ± 1

2 ± 1

0.001a

Oral dryness (score 0/1/2/3)

0/3/4/13

20/0/0/0

<0.001b


* The time from established diagnosis to present examination. Patients were interviewed regarding their intake of medicines. Their intake of xerogenic medicines included antidepressants, antihistamines and β-blocking agents [20]. §Patients were also interviewed regarding their smoking habits, since cigarette smoking has been shown to reduce the extent of labial salivary gland lymphocytic infiltration [23] and to have a negative impact on periodontal status. Smoking, however, has no impact on salivary flow or composition [24].

P-values obtained by a two-sample t-test (a) and Fisher exact test (b). NA; not analyzed.

Pedersen et al. BMC Clinical Pathology 2005 5:4   doi:10.1186/1472-6890-5-4

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