Table 1

pThr187-p27, "plain"-p27 and MIB-1 expression in normal tissues.

Tissue type

Phospho-p27

"plain"-p27

MIB-1


Normal squamous epithelium skin, tonsil, larynx, cervix.

Parabasal layer

+++

-

++++

intermediate

-

++++

+

Granular layer

-

+++

-

Germinal centers Tonsil, lymphnode, apendix

Mantle cells

-

++++

-

Centroblasts

+++

-

++++

Centrocytes

-

+++

-

Bowel Crypt cells

Deep

+++

-

++++

superficial

-

++++

-

Placenta

trophoblast

+++

-

++++

syncytiotrofoblast

-

++++

-

Kidney

+/-

+++

+/-

Lung

+/-

+++

+/-

Thyroid

+/-

+++

+/-

Prostate

+/-

+++

+/-


Key: ++++ >80% of positive cells.

+++ 50–80% of positive cells

++ 10–50% of positive cells

+ <10% of positive cells

+/- Only occasional staining

- Negative staining

Troncone et al. BMC Clinical Pathology 2005 5:3   doi:10.1186/1472-6890-5-3

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