Representative deletion mapping: LOH at 4 loci, D1S508, D1S2734, D19S219 and D19S412, in tumors from four different patients (panels A, B, C, D). Comparison between the patient's constitutional DNA (N) and tumor DNA (T) reveals in panel A, a loss of allele 1 in the tumor DNA; in panel B, loss of allele 1; in panel C, loss of allele 2 and in panel D, loss of allele 2. A faint band was sometimes observed in lanes with tumor DNA, most likely reflecting some minimal contamination with normal DNA. M = molecular weight marker; 1 = allele 1; 2 = allele 2.
Myal et al. BMC Clinical Pathology 2003 3:6 doi:10.1186/1472-6890-3-6