Figure 8.

CIN II Lesion Hybridized with HPV Probe. A. A CIN II lesion hybridized with DAKO wide-spectrum probe and incubated with AEC for 10 minutes. Diffuse and punctate signals are evident (arrows). B. Tissue from the same lesion incubated with DAB for 3 minutes. Diffuse and puncate signals are evident but there are also numerous punctate-like signals not associated with cell nuclei that compromise interpretation. Scale Bar: 10μm