Absence of CD26 expression is useful in isolating neoplastic T-cell populations. A. Non-neoplastic PB shows normal variable expression of CD26 in CD4(+) T-cells. B. The forward/side scatter histogram from a case of MF in PB. Aberrant events representing neoplastic cells are painted red and phenotypically normal CD4 and CD8 T-cell populations are painted green. C. CD4/CD26 histogram shows a discrete uniformly CD26(-) abnormal T-cell population representing tumor cells.
Washington et al. BMC Clinical Pathology 2002 2:5 doi:10.1186/1472-6890-2-5