Table 3

Univariate analyses of disease progresssion (n =158)
Variable Categorization Tumor progression
na events pb
Pathologic data:
Tumor stage (WHO 1973c)
pTa 85 10 0.412
pT1 68 12
Histologic grade (WHO 1973c)
G1 43 3 0.093
G2 82 12
G3 28 7
Histologic grade (WHO 2004d)
Low grade 95 10 0.092
High grade 58 12
Adjacent carcinoma in situ
No 141 20 0.570
Yes 12 2
Multifocality
Unifocal tumor 111 15 0.486
Multifocal tumor 42 7
Growth pattern
Papillary 146 17 <0.0001
Solid 7 5
Immunohistochemistry:
HDAC-1
Low expression 92 9 0.085
High expression 61 13
HDAC-2
Low expression 88 12 0.628
High expression 65 10
HDAC-3
Low expression 65 8 0.754
High expression 88 14
Ki-67 IHC
Low expression 101 9 0.004
High expression 52 13

aOnly primary pTa and pT1 tumours are included.

bLog Rank test (2-sided); bold face representing p-values <0.05.

cStaging and grading according to the 1973 WHO classification system.

dStaging and grading according to the 2004 WHO classification system.

Poyet et al.

Poyet et al. BMC Clinical Pathology 2014 14:10   doi:10.1186/1472-6890-14-10

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