Table 4

Univariate and multivariate analyses of overall survival in patients with hormone receptor-positive/HER2-negative primary breast cancer
Univariate Multivariate
Total Hazard (95% CI) P-value Hazard (95%CI) P-value
(n=142) ratio ratio
Ki67-p53 Low Ki67 LI and Negative p53 88 1 1
High Ki67 LI and/or Positive p53 54 8.8 1.9-40.4 0.0049 7.9 1.7-36.7 0.0081
FOXA1 Low 20 1
High 119 0.49 0.06-3.9 0.50
GATA3 Negative 30 1
Positive 112 1.1 0.31-4.3 0.84
Basal phenotype marker Negative 9 1
(CK5/6, CK14, EGFR) Positive 133 1.2 0.15-9.3 0.86
P-cadherin Low 90 1
High 52 1.8 0.57-5.5 0.32
Tumor size <5.0cm 17 1
≧5.0cm 122 3.4 0.90-12.8 0.071
Lymph-node metastasis (−) 80 1
(+) 59 3.9 1.02-14.7 0.045
Nuclear grade 1, 2 111 1
3 31 3.8 1.2-11.9 0.0020
Chemotherapy No 93 1
Yes 49 2.0 0.65-6.3 0.22

Abbreviation: 95%CI 95% confidence interval, LI labeling index.

Kobayashi et al.

Kobayashi et al. BMC Clinical Pathology 2013 13:5   doi:10.1186/1472-6890-13-5

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