Table 2

Uni- and multivariate analyses
Expression Univariate analysis Multivariate analysisa
HR (95% CI) p HR (95% CI) p
GAPDH PFI low (<0.25), n = 18 1 1
high (≥0.25), n = 37 2.1 (1.1-4.0) 0.031 2.1 (1.0-4.5) 0.043
OS low (<0.25), n = 18 1 1
high (≥0.25), n = 37 2.8 (1.2-6.5) 0.015 2.3 (1.0-5.6) 0.063
PKM2 PFI low (<0.70), n = 18 1 1
high (≥0.70), n = 37 1.2 (0.7-2.3) 0.55 1.5 (0.8-2.8) 0.27
OS low (<0.70), n = 18 1 1
high (≥0.70), n = 37 1.1 (0.5-2.2) 0.87 1.2 (0.6-2.6) 0.60
ATP5B PFI low (<0.31), n = 18 1 1
high (≥0.31), n = 37 1.7 (0.9-3.3) 0.089 1.8 (0.9-3.6) 0.097
OS low (<0.31), n = 18 1 1
high (≥0.31), n = 37 2.6 (1.1-5.9) 0.025 2.3 (1.0-5.3) 0.062
BEC-index PFI low (≤2.65), n = 36 1 1
high (>2.65), n = 19 0.46 (0.23-0.92) 0.028 0.47 (0.23-0.95) 0.035
OS low (≤2.65), n = 36 1 1
high (>2.65), n = 19 0.42 (0.20-0.94) 0.033 0.49 (0.22-1.31) 0.088

Abbreviations: HR, hazard ratio, CI, confidence interval.

aMultivariate model with adjustment for age, FIGO stage, grade and postoperative residual tumor size.

Platinum-free interval (PFI) and overall survival (OS) in relation to mRNA expression of GAPDH, PKM2, ATP5B and BEC-index.

Hjerpe et al.

Hjerpe et al. BMC Clinical Pathology 2013 13:30   doi:10.1186/1472-6890-13-30

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