Figure 2.

Frequency of ALDH+ cells in ductules of benign breast tissue from pre-menopausal women with a family history of breast cancer. ALDH+ cells were detected significantly more often in tissue from patients in this group than in control patients. A, Representative image of ALDH+ cell populations (arrows) in breast tissue from a woman with a family history of breast cancer but no BRCA1/2 mutation. ALDH+ cells in the periphery of blood vessels, such as in the large Y-shaped structure in the center of this image, were detected in some cases (not analyzed further in this study). B, Image demonstrating ALDH+ cell populations (arrows) in benign breast tissue from a woman with a BRCA1 mutation. C, Image showing ALDH+ cell populations (arrows) in benign breast tissue from a woman with a BRCA2 mutation. Scale bar in A represents 100 μm in all three images.

Isfoss et al. BMC Clinical Pathology 2013 13:28   doi:10.1186/1472-6890-13-28
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