Table 3

Correlations between the expression of EphA2, EphA4, and ephrinA1 and clinicopathological factors
EphA2 EphA4 ephrinA1
low high p low high p low high p
n 77 145 111 111 107 115
Age
  <70 142 53 89 0.27 75 67 0.26 72 70 0.32
  ≥70 80 24 56 36 44 35 45
Gender
  female 54 17 37 0.57 32 22 0.12 29 25 0.35
  male 168 60 108 79 89 78 90
Main location
  middle or lower 177 66 111 0.11 89 88 0.87 92 85 0.025
  upper 45 11 34 22 23 15 30
WHO pathological type
  differentiated 107 35 72 0.55 54 53 0.89 48 59 0.34
  undifferentiated 115 42 73 57 58 59 56
Depth of invasion
  T1/2 118 59 59 <0.001 85 33 <0.001 69 49 0.001
  T3/4 104 18 86 26 78 38 66
Lymphatic invasion
  negative 69 35 34 0.001 51 18 <0.001 47 22 <0.001
  positive 153 42 111 60 93 60 93
Venous invasion
  negative 73 39 34 0.001 55 18 <0.001 52 21 <0.001
  positive 149 38 111 56 93 55 94
Lymph node metastasis
  negative (N0) 114 54 60 0.001 77 37 <0.001 65 49 0.007
  positive (N1/2/3) 108 23 85 34 74 42 66
Stage
  I / II 142 66 76 <0.001 95 47 <0.001 80 62 0.001
  III/IV 80 11 69 16 64 27 53
Distant metastasis or recurrence
  negative 152 69 83 <0.001 99 53 <0.001 81 71 0.025
  positive 70 8 62 12 58 26 44

Miyazaki et al.

Miyazaki et al. BMC Clinical Pathology 2013 13:19   doi:10.1186/1472-6890-13-19

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