Hematoxylin and eosin (A) as well as immunochemical stainings (B-F) of the current lymph node biopsy from 2011. Effacement of the normal lymph node architecture by medium-sized atypical lymphocytes. Evidence of expanded mesh works of follicular dendritic cells stained by CD23 (B). Neoplastic cells show strong positivity for CD3 (C) and CD4 (D) as well as positivity for PD-1 (E) and CXCL13 (F).
Banz et al. BMC Clinical Pathology 2013 13:18 doi:10.1186/1472-6890-13-18