Table 2

Analysis of the expression of genes according to the categorization of covariates with descriptions of the fold regulation and statistical differences (Mann–Whitney U test; p values are shown in parentheses) in the study cohort (n = 114)
Covariates Comparison performed Genes
Control vs. test group ITGA3 ITGA5 ITGA6 ITGB5 ITGAV
FR ( p ) FR ( p ) FR ( p ) FR ( p ) FR ( p )
Gender Female vs. male - 1.81 (0.377) 1.20 (0.467) 1.22 (0.599) 1.04 (0.360) 1.17 (0.068)
Age <60 vs. ≥60 years 1.27 (0.301) -1.54 (0.016) 1.15 (0.524) 1.14 (0.267) -1.22 (0.128)
Histological classification Adeno. vs. mucinous 4.02 (0.700) 1.25 (0.029) -1.05 (0.358) 1.34 (0.815) -1.02 (0.983)
Tumor grading Low vs. high grade 2.94 (0.752) 1.88 (0.05) -1.34 (0.098) 1.36 (0.889) 1.08 (0.371)
Venous invasion Absent vs. present 1.78 (0.653) -1.13 (0.510) 1.42 (0.047) 1.12 (0.718) 1.02 (0.818)
Lymphatic vessel invasion Absent vs. present 1.18 (0.619) -1.47 (0.119) 1.10 (0.878) -1.03 (0.643) -1.03 (0.914)
Perineural invasion Absent vs. present -4.11 (0.782) 1.00 (0.971) 1.36 (0.544) -1.74 (0.686) 1.37 (0.028)
Clinical stage (TNM) I vs. III 2.40 (0.025) 1.08 (0.642) - 1.47 (0.869) 1.30 (0.042) 1.14 (0.348)

FR, Fold regulation; Adeno., Adenocarcinoma. Significant values are bold.

Denadai et al.

Denadai et al. BMC Clinical Pathology 2013 13:16   doi:10.1186/1472-6890-13-16

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