Table 1

Histological features of 27802 cases from 1990 to 2009
N (%) M F Ma(yrs) Ma(yrs)
I. Tumors of neuroepithelial tissue
  1. Astrocytic tumors
   Pilocytic astrocytoma 469 (1.69) 253 214 21.1 17
   Pilomyxoid astrocytoma 20 (0.07) 8 12 19.2 17
   Subependymal giant cell astrocytoma 27 (0.10) 15 12 16.2 13
   Pleomorphic xanthoastrocytoma 67 (0.24) 33 34 28.4 23
   Glioblastoma 2170 (7.81) 1362 805 50.2 53
   Giant cell glioblastoma 12 (0.04) 9 3 42.7 41
   Gliosarcoma 64 (0.23) 39 25 48.8 50.5
   Anaplastic astrocytoma 939 (3.38) 593 346 49.2 42
   Gliomatosis cerebri 3 (0.01) 2 1 59 62
  2. Oligodendroglial tumors
   Oligodendroglioma 990 (3.56) 555 426 38.6 39
   Anaplastic oligodendrogliom 534 (1.92) 313 221 43.5 44
  3. Oligoastrocytic tumors
   Oligoastrocytoma 243 (0.87) 143 100 38.9 39
   Anaplastic oligoastrocytoma 89 (0.32) 56 33 44.7 46
  4. Ependymal tumors
   Ependymoma 623 (2.24) 350 273 37 38
   Subependymoma 39 (0.14) 21 18 43 43
   Anaplastic ependymoma 223 (0.80) 129 93 30 30
  5. Choroid plexus tumor
   Choroid plexus papilloma 91 (0.33) 34 57 29 29
   Atypical choroid plexus papilloma 2 (0.01) 0 2 37.5 37.5
   Choroid plexus carcinoma 11 (0.04) 8 3 31.6 25
  6. Other neuroepithelial tumors
   Chordoid glioma of the third ventricle 3 (0.01) 1 2 31.3 27
   Astroblastoma 4 (0.01) 2 2 37.8 42
  7. Neuronal and mixed neuronal-glial tumors
   Cerebellar liponeurocytoma 1 (0.00) 1 0 59 59
   Desmoplastic infantile astrocytoma/ganglioglioma 5 (0.02) 1 4 16.8 11
   Dysembryoplastic neuroepithelial tumor 54 (0.19) 34 20 22.6 17.5
   Dysplastic gangliocytoma of cerebellum, Lhermitte-Duclos 7 (0.03) 3 4 28.7 38
   Rosette-forming glioneuronal tumor of the fourth ventricle 4 (0.01) 0 4 28.3 24
   Paraganglioma 29 (0.10) 14 15 42.5 42
   Papillary glioneuronal tumor 13 (0.05) 9 4 32.4 29
   Anaplastic ganglioglioma 43 (0.15) 26 17 39.7 41
   Gangliocytoma 40 (0.14) 29 11 29.6 31.5
   Ganglioglioma 137 (0.49) 87 49 33.1 32
   Central neurocytoma 131 (0.47) 63 68 30.2 29
  8. Tumors of pineal region
   Papillary tumor of the pineal region 2 (0.01) 1 1 31.5 31.5
   Pineocytoma 15 (0.05) 5 10 30.3 22
   Pineal parenchymal tumor of intermediate differentiation 5 (0.02) 5 0 26.8 20
   Pineoblastoma 10 (0.04) 5 5 25.6 17.5
  9. Embryonal tumors
   Medulloblastoma 515 (1.85) 329 183 15.4 12
   PNET 119 (0.43) 75 43 21.9 17
   Atypical teratoid/rhabdoid tumor 4 (0.01) 2 2 21.8 23
II. Tumors of cranial and paraspinal nerves
  1. Schwannoma (neurilemoma, neurinoma) 3499 (12.59) 1754 1736 45 45
  2. Neurofibroma 166 (0.60) 106 60 36.3 38
  3. Perineurioma 1 (0.00) 0 1 69 69
  4. MPNST 26 (0.09) 11 15 37.8 42
III. Tumors of meninges
  1. Tumors of meningothelial cells
   Grade I meningothelial cells tumors 7623 (27.42) 2294 5309 50.7 51
   Atypical 359 (1.29) 184 173 51.2 52
   Chordoid 16 (0.06) 8 8 48.5 51
   Clear cell 30 (0.11) 13 17 37.5 39.5
   Papillary 26 (0.09) 16 10 36.7 35.5
   Rhabdoid 15 (0.05) 9 6 42.2 42
   Anaplastic, malignant 235 (0.85) 129 105 50.3 50
  2. Mesenchymal tumors
   Hemangiopericytoma 202 (0.73) 112 88 43.3 42
   Anaplstic hemangiopericytoma 8 (0.03) 5 3 48.3 45.5
   Other Mesenchymal tumors 825 (2.97) 450 369 36 37
  3. Primarymelanocytic lesions
   Diffuse melanocytosis 2 (0.01) 1 1 35.5 35.5
   Melanocytoma 9 (0.03) 5 4 47 47
   Malignantmelanoma 31 (0.11) 21 10 42.2 42
  4. Other neoplasms related to the meninges
   Hemangioblastoma 760 (2.73) 463 293 40.8 40
IV. Lymphomas and hematopoietic neoplasms 464 (1.67) 272 191 49.7 52
V. Germ cell tumors
  1. Germinoma 204 (0.73) 148 56 17.4 16
  2. Embryonal carcinoma 14 (0.05) 12 2 12.2 12.5
  3. Yolk sac tumor 2 (0.01) 2 0 7 7
  4. Choriocarcinoma 1 (0.00) 0 1 34 34
  5. Teratoma 10 (0.04) 8 2 14.5 14
   Mature 56 (0.20) 36 20 23.5 20.5
   Immature 22 (0.08) 20 2 16 14.5
   With malignant transformation 4 (0.01) 4 0 13.3 14
  6. Mixed germ cell tumors 35 (0.13) 29 6 16.6 14
VI. Tumors of the sellar region
   Craniopharyngioma 1144 (4.11) 665 477 32.1 33
   Granular cell tumor 7 (0.03) 2 5 49 52
   Pituicytoma 1 (0.00) 1 0 45 45
   Spindle cell oncocytoma of the adenohypophysis 1 (0.00) 1 0 24 24
VII. Metastatic tumors 1431 (5.15) 890 536 53.9 55
Total 27802 13945 13774

N = Number; M = Male; F = Female;

Ma = Median age at diagnosis; ma = Mean age at diagnosis;

PNET = Primitive neuroectodermal tumor;

Grade I meningothelial cells tumors = Meningiothelial; Fibrous, fibroblastic; Transitional, mixed; Psammomatous; Angiomatous; Microcystic; Secretory; Lymphop lasmacyte-rich; Metaplastic.

Other mesenchymal tumors = Lipoma; Angiolipoma; Hibernoma; Liposarcoma; Solitary fibrous tumor; Fibrosarcoma; Malignant fibrous histiocytoma; Leiomyoma; Leiomyosarcoma; Rhabdomyoma; Rhabdomyosarcoma; Chondroma; Chondrosarcoma; Osteoma; Osteosarcoma; Osteochondroma; Hemangioma; Angiosarcoma; Kaposi sarcoma; Ewing sarcoma-PNET.

MPNST = Malignant peripheral nerve sheath tumor.

Chen et al.

Chen et al. BMC Clinical Pathology 2013 13:14   doi:10.1186/1472-6890-13-14

Open Data