Manual and automated HER2 testing in breast carcinoma. Results obtained by manual and automated HER2 testing using the same area of carcinoma are shown. Each carcinoma (n = 100) is depicted in the graphs according to the HER2 copy number (A), CEP17 copy number (B), HER2/CEP17 ratio (C) and proportion of carcinoma cells with HER2/CEP17 ratio >2.2 (D), respectively. Slope, intercept, and R square values of regression curves are summarized in Table 2.
Öhlschlegel et al. BMC Clinical Pathology 2013 13:13 doi:10.1186/1472-6890-13-13