Table 6

Results of Cox regression analysis summarizing significant independent prognostic factors in patients with soft tissue sarcomas
Tumor, N=249 Capsule, N=80
Factor Hazard Ratio 95% CI P Hazard Ratio 95% CI P
Nationality
 Norwegian 1.000 1.000
 Russian 0.948 0.603-1.490 0.816 0.588 0.263-1.312 0.194
Tumor size
 < 5 cm 1.000 0.540* 1.000 0.342*
 5-10 cm 1.103 0.687-1.770 0.685 0.888 0.376-2.099
 > 10 cm 1.310 0.797-2.153 0.287 1.671 0.660-4.233
Malignancy grade FNCLCC
 1 1.000 0.001* 1.000 0.051*
 2 1.997 1.129-3.531 0.017 1.402 0.383-5.137 0.610
 3 2.874 1.617-5.107 <0.001 2.954 0.837-10.432 0.092
Metastasis at time of diagnosis
 No 1.000 1.000
 Yes 2.842 1.855-4.354 <0.001 2.101 0.901-4.898 0.086
Resection margins
 Wide 1.000 1.000
 Non-wide 2.523 1.706-3.730 <0.001 2.245 1.077-4-680 0.031
Ki67
 Low 1.000 0.432* 1.000
 Medium 1.059 0.528-2.163 0.876 - - -
 High 1.365 0.710-2.625 0.351 2.553 1.167-5.584 0.019
M-CSF
 Low 1.000 NIA
 High 0.815 0.463-1.435 0.478
TGF-beta
 Low 1.000 NIA
 High 0.682 0.247-1.881 0.460
M-CSF and TGF-beta
 Low 1.000 NIA
 High 1.532 1.062-2.208 0.022

* Overall significance as a prognostic factor. NIA = Not included in analysis.

Sorbye et al.

Sorbye et al. BMC Clinical Pathology 2012 12:7   doi:10.1186/1472-6890-12-7

Open Data