Table 2

Diagnostic performance of the tests for high-risk lesions

Protocol

Parameter

Compared to HPMV

Using LCA


CHEM

Sensitivity

1.00 (0.82-1.00)

1.00 (0.99-1.00)


Specificity

0.01 (0.00-0.06)

0.01 (0.00-0.04)


TBLU

Sensitivity

0.59 (0.36-0.78)

0.99 (0.92-1.00)


Specificity

0.79 (0.69-0.87)

1.00 (0.99-1.00)


CHTB

Sensitivity

0.59 (0.36-0.78)

1.00 (0.99-1.00)


Specificity

0.78 (0.68-0.86)

1.00 (0.99-1.00)


HPMV

Sensitivity

---

0.37 (0.19-0.55)


Specificity

---

0.90 (0.83-0.97)


Prevalence of HRL

0.17 (0.10-0.24)

0.27 (0.18-0.36)


CHEM, chemiluminescence; TBLU, toluidine blue retention; CHTB, toluidine blue retention and chemiluminescence; HPMV, histopathology majority vote; LCA, latent class analysis; HRL, high risk lesion

Ujaoney et al. BMC Clinical Pathology 2012 12:6   doi:10.1186/1472-6890-12-6

Open Data