Table 3

Cross tabulation of HER2 gene status for CISH versus Dako FISH.

HER2 FISH pharmDx™


Non-amplified

Amplified

Total


HER2 CISH pharmDx™

Non-amplified

301

3

304

Amplified

3

41

44

Total

304

44

348


Two tailed 95% confidence intervals are based on the binomial distribution. Overall agreement: (342/348 × 100) = 98.3% (CI95: 96.5%; 99.3%), Positive agreement: (41/44 × 100) = 93.2% (CI95: 82.9%; 98.0%), Negative agreement: (301/304 × 100) = 99.0% (CI95: 97.4%; 99.7%) and Kappa: 0.92 (SE: 0.03)

Mollerup et al. BMC Clinical Pathology 2012 12:3   doi:10.1186/1472-6890-12-3

Open Data