Table 2

Demographics of the 5 patients missed by the Siemens FLC assay
Patient MM type Freelite Siemens Missed FLC* Misclassified FLC as <500 mg/L**
κ λ Ratio κ λ Ratio
2 Free λ 2 7010 0.0003 1 322 0.003 No Yes
7 IgA λ 8 1810 0.0044 4 1 8.058 Yes Yes
10 IgG λ 8 1080 0.0078 9 64 0.134 No Yes
13 IgG λ 9 572 0.0162 9 225 0.041 No Yes
23 IgG κ 796 6 125.7 493 17 29.6 No Yes

*Patients were classified as missed FLC if the new assays did not identify a monoclonal FLC.

**Patients were classified as misclassified if their monoclonal FLC level was reported as less than the nephrotoxic level of 500 mg/L (5 of 28 patients).

Hutchison et al.

Hutchison et al. BMC Clinical Pathology 2012 12:12   doi:10.1186/1472-6890-12-12

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