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Open Access Case report

Intranodal palisaded myofibroblastoma originating from retroperitoneum: an unusual origin

Jayesh Sagar1*, Athanasia Vargiamidou1 and Hemachandran Manikkapurath2

Author Affiliations

1 Department of Surgery, Royal Sussex County Hospital, Brighton. BN2 5BE, UK

2 Department of Cellular Pathology, Stoke Mandeville Hospital, Aylesbury. HP21 8AL, UK

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BMC Clinical Pathology 2011, 11:7  doi:10.1186/1472-6890-11-7

Published: 30 June 2011



Intranodal palisaded myofibroblastoma is one of the primary mesenchymal tumours. The inguinal region is the commonest site of this rare tumour. As there are only about 55 such cases reported in the literature, the precise aetiology and pathogenesis have yet to be explained adequately. Here we report a case of a 72 year old man presented with incidental finding of intranodal palisaded myofibroblastoma in the retroperitoneal region.

Case Presentation

A 72-year old man presented with abdominal pain in right upper quadrant with an incidental finding of abdominal mass in the right flank. The computerised tomogram scan of abdomen confirmed acute cholecystitis with a 5 x 5 cm retroperitoneal mass. He underwent cholecystectomy with excision of this mass. He recovered well following his operation and was discharged from the hospital. Histological examination confirmed the diagnosis of intranodal palisaded myofibroblastoma.


To our knowledge, this is the first case of intranodal palisaded myofibroblastoma originating from retroperitoneum. Along with the rarity of this case, we also discussed its typical histopathological findings, aetiology and pathogenesis.

Intranodal palisaded myofibroblastoma; retroperitoneum; lymph nodes