Additional file 3.
FAK, E-cadherin and p63 expression are specifically altered in tumors and metastases. A, A significant inverse relationship was found between E-cadherin and FAKc expression. Spearman's rank correlation and 95% confidence interval are shown. The relationship was not significant for tumors only. B, FAKc; C, E-cadherin and D, p63 are significantly different in tumors and metastases compared to mucosa adjacent to tumor. An arrow in D indicates the p63-negative metastasis of case 2. E, p63 is not significantly altered with respect to SNAI1 expression levels in the majority of OSCC. However, two cases with sarcomatoid component show p63 loss and SNAI1-positivity. (Open and black symbols in diagrams B-E correspond to case 1 and 2, respectively).
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Schwock et al. BMC Clinical Pathology 2010 10:1 doi:10.1186/1472-6890-10-1