SNAI1 expression occurs in tumor cells, tumor-associated stroma and endothelium. A, SNAI1 expression (arrow) in an OSCC with 5% positivity in the tumor cells of the primary site. B, SNAI1 expression (arrows) in an OSCC with 20% positivity in the tumor cells of the primary site. C, Vimentin (cytoplasmic, red) and SNAI1 (nuclear, brown) show co-expression in stromal cells with fibroblastic morphology. D, HMWK (cytoplasmic, red) in strands of diffusely infiltrating OSCC and SNAI1 are mutually exclusive. E, SNAI1 in endothelium in the vicinity of the same OSCC shown in C and D.
Schwock et al. BMC Clinical Pathology 2010 10:1 doi:10.1186/1472-6890-10-1