Table 1

General animal characteristics parameters in the control group and in rats treated with MCT (i.p; Heart failure) or with MCT + C. Dactylon rhizomes hydroalcoholic extract (orally).

Parameter

Untreated

Treated with Digoxin

Treated with C. dactylon extract


Control

MCT

0.01 mg/kg

50 mg/kg

100 mg/kg

200 mg/kg


Baseline BW (g)

151 ± 12

150 ± 10

144 ± 9

147 ± 11

143 ± 9

152 ± 13

Δ BW (g)

57 ± 6

26 ± 9

38 ± 11*

32 ± 9

40 ± 6*

43 ± 11**

Ventricles Wet to Dry weight ratio

4.35 ± 0.3

5.0 ± 0.13

4.64 ± 0.3*

4.61 ± 0.26*

4.50 ± 0.27**

4.52 ± 0.25**

Wet ventricle weight to Body weight ratio (g/kg)

3.31 ± 0.3

4.9 ± 0.7

4.6 ± 0.7

4.9 ± 1.3

4.2 ± 0.8

3.25 ± 0.3**

Lung Wet to Dry weight ratio

3.98 ± 0.18

4.98 ± 0.41

4.76 ± 0.21

4.69 ± 0.41

4.70 ± 0.22

4.46 ± 0.25**

Wet Lung weight to Body weight ratio (g/kg)

5.01 ± 0.83

8.90 ± 2.9

10.82 ± 2.9

10.03 ± 2.9

8.33 ± 3.4

4.78 ± 0.87**

Mortality (%)

0

20

40

20

20

10


Data is expressed as mean ± SD.

Baseline BW, body weights immediately prior to extract administration; Δ BW, increase in body weight over 2-weeks treatment period. All other values obtained 4 weeks after MCT administration. Treatments were started 2 weeks after MCT administration and continued for 2 weeks. † p < 0.01 from respective control value; *p < 0.05; **p < 0.01 from MCT treated group using one way ANOVA.

Garjani et al. BMC Complementary and Alternative Medicine 2009 9:28   doi:10.1186/1472-6882-9-28

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