Continuous ginger exposure inhibits growth in ovarian cancer cells in vitro. A, B, C: The effect of ginger on growth of A2780, SKOV3 and ES2 ovarian cancer cell lines was assessed by using sulforhodamine B assays. Cells were incubated continuously with media containing ginger at the indicated concentrations and growth was assayed at Days 1, 3 and 5 of exposure. Ginger treated cells displayed significant growth inhibition as compared to control treated cells (p < .05 for all cell lines, all ginger concentrations). D: Human ovarian surface epithelial cells were treated with the indicated concentrations of ginger with minimal effect seen following days 1–3 of culture (p > .05). HOSE demonstrated some inhibition of growth by day 5 of treatment (p < .05). Data are presented as means ± S.D, and are representative of at least 3 independent experiments.
Rhode et al. BMC Complementary and Alternative Medicine 2007 7:44 doi:10.1186/1472-6882-7-44