Table 2

Dosage effect of MAK-4 and MAK-5 on H-ras-induced cell transformation in Rat 6 cells
Treatment
 Exogenous H-ras gene
 Cytotoxicity (% survival)
 Relative number of foci
Mock control
 -
 100
 0
None
 +
 100
 1.0
MAK-4:


200 μg/ml
 +
 132
 1.75
500 μg/ml
 +
 98
 1.29
1000 μg/ml
 +
 92
 1.35
MAK-5:


200 μg/ml
 +
 135
 0.69
500 μg/ml
 +
 64
 0.28
1000 μg/ml
 +
 48
 0.26

Data were obtained from two individual experiments by focus formation assay. Triplicate plates were used for each experiment. Experimental procedures were the same as indicated in Table 1.

Penza et al. BMC Complementary and Alternative Medicine 2007 7:19   doi:10.1186/1472-6882-7-19