Figure 2.

Effects of treatments on macrophage infiltration. (A) Immunohistochemistry staining for macrophage (ED-1-positive cells) in the renal tissues of STZ-diabetic rats. STZ-diabetic rats were dosed by oral gavage once per day for eight weeks with 200 mg/kg PSLR (STZ + PSLR 200) or 300 mg/kg PSLR (STZ + PSLR 300). Normal or STZ-diabetic rats receiving vehicle treatment were given the same volume of vehicle (distilled water) used to to disperse PSLR. Arrows indicate ED-1-positive cells. (B) Quantification results are shown for number of macrophages (ED-1-positive cells). Values (mean ± SD) were obtained for each group of 4 animals. bP < 0.01 compared to the values of vehicle-treated normal rats (normal + vehicle). cP < 0.05 and dP < 0.01 compared to the values of vehicle-treated STZ-diabetic rats (STZ + vehicle), respectively.

Lu et al. BMC Complementary and Alternative Medicine 2014 14:156   doi:10.1186/1472-6882-14-156
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