Relaxation responses induced by MEPY in endothelium-intact rat aortic rings pre-contracted with phenylephrine (PE, 1 μM) in the presence or absence (control) of Nω -Nitro-L-arginine methyl ester (L-NAME, 10 μM), methylene blue (MB, 10 μM), or 1-H-[1,2,4]-oxadiazolo-[4,3-α]-quinoxalin-1-one (ODQ, 10 μM) in Krebs-Henseleit solution. The relaxant effects of MEPY on isolated rat aortic rings were calculated as a percentage of the contraction in response to PE. Values are expressed as mean ± SEM (n = 6–8). *P < 0.05, **P < 0.01 vs. control.
Lee et al. BMC Complementary and Alternative Medicine 2013 13:31 doi:10.1186/1472-6882-13-31