Table 4

Different types of chromosomal damage induced by MMS (40 mg/kg b. w.) and different extracts (300 mg/kg b.w.) from Cyperus rotundus in bone marrow cells of male Balb/c mice
Treatment ctb csb del r cf ra Total aberrationsa
Solvent control : Tween-80 (1%) - 1 - 6 6 - 13 ± 0.58
Methyl methansulfonate (MMS) - 16 - 17 12 - 44 ± 3.06
TOF enriched extract - 3 - 3 3 - 9 ± 1.53
Aqueous extract - 4 - 4 2 - 10 ± 0.62
Methanolic extract - - - 3 11 - 14 ± 0,58
Solvent control : Tween-80 (5%) - - - 10 7 - 17 ± 1.15
Ethyl acetate extract - 2 - 12 5 - 19 ± 1.53

ctb = chromatid break, csb = chromosome break, del = deletion, r = ring, cf = centric fusion, ra = rearrangements.

aTotal aberrations (mean ± standard error of the mean from one hundred cells were analyzed per animal for a total of 500 cells per treatment).

Soumaya et al.

Soumaya et al. BMC Complementary and Alternative Medicine 2013 13:28   doi:10.1186/1472-6882-13-28

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