Table 2

GI50, TGI and LC50 (μg/mL) for EAD and Dox
EAD Dox
Cancer cell lines GI50 TGI LC50 GI50 TGI LC50
U251 (glioma) 83.47 5.07 23.45
UACC-62 (melanoma) > 100 0.06 0.86
MCF7 (breast) 11.10 > 100 0.14 24.52
NCI/ADR-RES (ovarian resistance) 1.95 1.74 23.92
786-0 (renal) > 100 0.22 1.51
NCI-H460 (lung) 0.03 > 100 0.05
OVCAR-3 (ovarian) 6.38 0.30 1.72
HT29 (colon) 0.10 4.10 > 100 2.12 7.31 20.86
K-562 (leukemia) 31.13 0.90
Vero 1.40 11.36

EAD (crude methanol extract); dox (doxorubicin); GI50 (growth inhibitory activity); TGI (cytostatic activity); LC50 (cytotoxic activity); IC50 >100 (μg/mL) was considered not active.

Formagio et al.

Formagio et al. BMC Complementary and Alternative Medicine 2013 13:14   doi:10.1186/1472-6882-13-14

Open Data