Fenugreek extract induced plasma membrane rupture and total cell lysis. Increasing concentrations of fenugreek extract after 48 hr caused morphological changes leading to cell death. Disappearance of cell shape by rupture of plasma membrane was seen at higher concentrations of fenugreek extract. Arrows point to cellular membranes undergoing rupture. Pictures represent inverted light microscopic images taken at 400x magnification.
Al-Daghri et al. BMC Complementary and Alternative Medicine 2012 12:202 doi:10.1186/1472-6882-12-202