Table 6

Effect of Nuna kadugu on water consumption in experimental rats - repeated oral toxicity study
Treatment Sex      (ml)
1stWeek 2ndWeek 3stWeek 4stWeek 5thWeek 6thWeek
Control (0.5% CMC) M(n=5) 100.80±12.45 101.00±15.37 100.40±6.96 100.80±11.34
F (n=5) 98.40±5.53 101. 00±11.05 101.80±12.68 101.40±13.95
MF(n=10) 99.60±6.43 101.00±8.92 101.10±6.82 101.10±8.48
NK (300 mg/kg p.o/day) M(n=5) 99.40±11.42 100. 20±9.61 101.20±16.83 100.60±13.67
F (n=5) 101.60±5.71 101.40±11.28 100.60±9.09 101.60±11.51
MF(n=10) 100.50±6.03 100.80±6.99 100.90±9.02 101.10±8.42
(600 mg/kg p.o/day) M(n=5) 98.80±11.89 101.80±9.05 101.00±19.24 100.80±14.37
F (n=5) 100.00±7.29 100.80±8.00 102.20±17.30 100.40±11.21
MF(n=10) 99.40±6.58 101.30±5.70 101.60±12.20 100.60±8.59
(900 mg/kg p.o/day) M(n=5) 99.80±9.61 100.40±5.35 100.20±9.44 98.80±7.00
F (n=5) 100.20±12.48 99.80±6.97 99.60±6.10 101.20±16.49
MF(n=10) 100.00±7.43 100. 10±4.14 99.90±5.30 100.00±8.45
Satellite group
Control (0.5% CMC) M(n=5) 101.60±8.35 102.60±7.12 100.80±15.63 102.40±13.55 101.40±10.62 100.40±19.44
F (n=5) 99.40±4.15 100.20±5.84 100.00±10.43 99.00±5.55 100.40±8.44 101.60±18.25
MF(n=10) 100.50±4.41 101.40±4.36 100.40±8.86 100.70±6.93 100.90±6.40 101.00±12.57
NK (900 mg/kg p.o/day) M(n=5) 101.60±8.39 101.40±10.63 101.60±14.66 101.20±4.04 102.40±11.78 101.60±10.80
F (n=5) 99.40±13.01 99.80±8.26 100.60±11.29 101.60±11.71 101.00±14.32 102.20±12.29
MF(n=10) 100.50±7.31 100.60±6.35 101.10±08.72 101.40±5.84 101.70±8.74 101.90±7.71

Values expressed as mean ± SEM; ml – milleliters; Significance with Tukey’s test following one way ANOVA is evaluated as *p < 0.05 and **p < 0.01 vs control group.

Ramaswamy et al.

Ramaswamy et al. BMC Complementary and Alternative Medicine 2012 12:190   doi:10.1186/1472-6882-12-190

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