Table 4

Effect of Nuna kadugu on body weight gain in experimental rats - repeated oral toxicity study
Treatment Sex      (g)
1stWeek 2stWeek 3stWeek 4stWeek 5thWeek 6thWeek
Control (0.5% CMC) M(n=5) 156.20±6.78 171.60±12.41 183.80±15.09 187.60±14.26
F (n=5) 155.4±10.3 157±7.75 166.6±4.80 169.6±4.54
MF(n=10) 155.8±5.82 164.3±7.32 175.2±8.00 178.6±7.67
NK (300 mg/kg p.o/day) M(n=5) 159.2±6.64 178.6±10.67 189.4±14.7 193.6±13.92
F (n=5) 143.0±2.16 148.4±3.64 157.4±3.45 160.0±3.49
MF(n=10) 151.10±4.26 163.50±7.32 173.40±8.90 176.80±8.78
(600 mg/kg p.o/day) M(n=5) 144.0±10.46 163.2±9.52 166.6±10.29 177.00±14.90
F (n=5) 142.40±10.27 159.40±11.85 163.00±10.13 177.80±11.06
MF(n=10) 143.20±6.89 161.30±7.19 164.80±6.83 177.40±8.74
(900 mg/kg p.o/day) M(n=5) 149.00±8.91 168.60±10.34 190.00±12.12 195.20±12.24
F (n=5) 139.60±5.23 146.80±4.67 157.20±6.86 161.60±6.99
MF(n=10) 144.3±5.11 157.7±6.46 173.6±8.54 178.40±8.68
Satellite group
Control (0.5% CMC) M(n=5) 141.00±12.54 164.80±16.47 169.80±17.46 174.60±17.57 178.40±20.52 185.00±18.43
F (n=5) 139.80±3.63 147.80±4.91 147.80±4.30 148.60±4.17 155.80±2.70 160.40±2.78
MF(n=10) 140.4±6.15 156.3±8.66 158.8±9.23 161.6±9.55 167.1±10.46 172.7±9.69
NK (900 mg/kg p.o/day) M(n=5) 152.6±11.56 170.2±12.50 181.2±8.25 179.6±13.95 182.2±12.85 188.2±9.68
F (n=5) 149.60±8.46 164.80±8.35 173.00±11.18 176.00±10.78 179.00±9.55 178.60±12.75
MF(n=10) 151.1±6.77 167.5±7.14 177.1±6.69 177.8±8.33 180.6±7.56 183.4±7.77

Values expressed as mean ± SEM; g – gram; Significance with Tukey’s test following one way ANOVA is evaluated as *p < 0.05 and **p < 0.01 vs control group.

Ramaswamy et al.

Ramaswamy et al. BMC Complementary and Alternative Medicine 2012 12:190   doi:10.1186/1472-6882-12-190

Open Data