Table 10

Effect of Nuna kadugu on organ weight of experimental Sprague Dawley rats in repeated oral toxicity study
Treatment Sex Organ Weight (gms)
Kidneys Adrenals Thymus Testis/Ovaries Epididymis
Control (0.5% CMC) M(n=5) 1.65±0.13 0.05±0.01 0.48±0.01 2.06±0.42 1.43±0.03
F (n=5) 1.34±0.13 0.04±0.00 0.48±0.03 0.08±0.02 -
MF(n=10) 1.49±0.10 0.04± 0.00 0.48±0.01 - -
NK (300 mg/kg p.o/day) M(n=5) 1.79±0.12 0.05±0.01 0.48±0.01 2.09±0.17 1.41±0.03
F (n=5) 1.35±0.04 0.05±0.01 0.49±0.02 0.32±0.02 -
MF(n=10) 1.57±0.09 0.05±0.00 0.48±0.01 - -
(600 mg/kg p.o/day) M(n=5) 1.61±0.10 0.04±0.00 0.47±0.02 1.96±0.19 1.47±0.03
F (n=5) 1.36±0.07 0.04±0.00 0.48±0.01 0.08±0.01 -
MF(n=10) 1.49±0.07 0.04±0.00 0.47±0.01 - -
(900mg/kg p.o/day) M(n=5) 1.64±0.14 0.04±0.00 0.47±0.01 2.22±0.38 1.49±0.03
F (n=5) 1.37±0.08 0.05±0.01 0.52±0.03 0.09±0.01 -
MF(n=10) 1.51±0.09 0.05±0.00 0.49±0.02 - -
Satellite group
Control (0.5% CMC) M(n=5) 1.51±0.12 0.05±0.01 0.46±0.02 1.98±0.43 1.41±0.03
F (n=5) 1.34±0.07 0.05±0.00 0.49±0.02 0.10±0.01 -
MF(n=10) 1.42±0.07 0.05±0.00 0.48±0.01 - -
NK (900 mg/kg p.o/day) M(n=5) 1.68±0.10 0.05±0.00 0.490.02 2.04±0.31 1.54±0.02
F (n=5) 1.35±0.05 0.05±0.00 0.51±0.03 0.12±0.00
MF(n=10) 1.51±0.08 0.05±0.00 0.50±0.02 1.98±0.43

Values expressed as mean ± SEM; n=10 (5/sex); Significance with Tukey’s test following one way ANOVA is evaluated as *p < 0.05 and **p < 0.01 vs control group.

Ramaswamy et al.

Ramaswamy et al. BMC Complementary and Alternative Medicine 2012 12:190   doi:10.1186/1472-6882-12-190

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