Table 3

Effect of Rutin on Genotoxicity studies
Treatment AgNORS (NORs/cell) %DNA fragmentation % oxo8dG % p53 % CYP 2E1
Control 2.02±0.33++ 5.33±1.46++ 4.10±0.53++ 7.13±0.63++ 15.23±1.09++
3 ml/kg CCl4 6.42±0.29** 22.50±3.68** 11.20±0.27** 3.41±0.49** 8.10±0.78**
50 mg/kg Rutin+CCl4 3.32±0.76++ 7.61±1.04++ 6.13±0.26++ 5.15±0.46++ 12.16±1.04++
70 mg/kg Rutin+CCl4 3.11±0.35++ 5.00±1.83++ 5.20±0.85++ 7.10±0.55++ 14.22±1.33++

Mean ±SE (n=6 number).

** indicate significance from the control group at P<0.01 probability level.

++ indicate significance from the CCl4 group at P<0.01 probability level.

Khan et al.

Khan et al. BMC Complementary and Alternative Medicine 2012 12:178   doi:10.1186/1472-6882-12-178

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