Table 5

Lipoxygenase activity of crude extracts and fractions of 6 plants from the Mascarene Islands
Concentrations (μg/mL) Lipoxygenase inhibition
Crude water extract Crude methanol extract Dichloromethane Ethylacetate n-butanol Water fraction
10 82.46 ± 10.09* 79.75 ± 10.07* 77.88 ± 6.37* 53.71 ± 4.17* 27.46 ± 1.77* 32.80 ± 1.31*
{97.06 ± 11.67*} {98.32 ± 7.64*} {81.21 ± 5.24*} {63.94 ± 3.13*} {74.98 ± 2.23*} {67.81 ± 4.47*}
[53.69 ± 2.36*] [38.88 ± 1.09*] [52.54 ± 0.95*] [53.31 ± 1.26*] [17.87 ± 1.01*] [48.64 ± 2.07*]
(13.59 ± 1.01) (23.03 ± 0.95*) (41.13 ± 1.68*) (30.96 ± 1.33*) (13.35 ± 0.67) (13.11 ± 0.67)
∫10.39 ± 0.96∫ ∫9.39 ± 1.01∫ ∫9.45 ± 0.34∫ ∫11.69 ± 0.66∫ ∫12.39 ± 1.03∫ ∫ 9.68 ± 0.91∫
∣1.23 ± 0.02 ∣ ∣5.62 ± 0.68∣ ∣0.96 ± 0.02∣ ∣2.36 ± 0.02∣ ∣14.96 ± 0.66*∣ ∣2.85 ± 0.51∣
5 69.37 ± 9.37* 62.69 ± 6.11* 58.37 ± 3.64* 28.67 ± 3.09* 11.09 ± 0.67 19.67 ± 0.99
{70.16 ± 5.55* } {83.67 ± 4.36*} {68.69 ± 2.01*} {42.67 ± 3.15*} {56.04 ± 2.16*} {46.39 ± 3.37*}
[37.11 ± 1.39*] [18.39 ± 2.67*] [29.67 ± 0.36*] [36.56 ± 0.76*] [9.36 ± 0.67] [32.05 ± 1.16*]
(7.51 ± 0.77) (16.37 ± 0.88*) (28.34 ± 1.09*) (14.36 ± 1.45*) (7.57 ± 0.84) (8.34 ± 0.34)
∫9.67 ± 0.82∫ ∫7.64 ± 0.36∫ ∫6.37 ± 0.22∫ ∫ 6.37 ± 0.98∫ ∫7.72 ± 0.23∫ ∫5.37 ± 0.62∫
∣0.96 ± 0.03∣ ∣2.37 ± 0.11∣ ∣0.57 ± 0.01∣ ∣1.09 ± 0.03∣ ∣ 7.09 ± 0.35∣ ∣1.06 ± 0.02∣
2.5 56.09 ± 7.67* 50.37 ± 3.07* 32.67 ± 1.06* 20.37 ± 2.01* 7.19 ± 0.65 9.37 ± 0.67
{53.37 ± 4.31*} {62.37 ± 3.16*} {50.37 ± 2.67*} {37.65 ± 1.11*} {39.67 ± 1.97*} {35.67 ± 2.01*}
[26.09 ± 1.03*] [10.09 ± 1.37] [13.06 ± 0.26] [27.39 ± 1.03*] [5.36 ± 0.58] [24.31 ± 1.09*]
(3.36 ± 0.17) (8.67 ± 0.36) (12.04 ± 1.11) (8.34 ± 0.67) (5.01 ± 0.11) (5.06 ± 0.25)
∫6.37 ± 0.66∫ ∫4.09 ± 0.46∫ ∫4.36 ± 0.07∫ ∫4.09 ± 0.54 ∫ ∫4.46 ± 0.33∫ ∫3.64 ± 0.36∫
∣0.67 ± 0.02∣ ∣1.06 ± 0.02∣ ∣0.36 ± 0.02∣ ∣0.67 ± 0.02∣ ∣4.53 ± 0.54∣ ∣0.97 ± 0.06∣
1.25 32.37 ± 2.07* 29.67 ± 2.01* 28.03 ± 0.45* 11.09 ± 0.37 2.37 ± 0.53 4.09 ± 0.36
{42.37 ± 2.01*} {48.69 ± 2.16*} {32.69 ± 1.97*} {13.39 ± 0.12} {26.67 ± 1.37*} {29.67 ± 1.36*}
[10.09 ± 0.96] [6.37 ± 0.65] [7.63 ± 0.11] [11.03 ± 0.15] [3.34 ± 0.27] [9.03 ± 0.37]
(1.55 ± 0.01) (5.34 ± 0.11) (9.37 ± 0.15) (5.34 ± 0.60) (2.09 ± 0.03) (2.04 ± 0.11)
∫2.39 ± 0.09∫ ∫1.96 ± 0.02∫ ∫2.34 ± 0.03∫ ∫2.39 ± 0.23∫ ∫1.07 ± 0.07∫ ∫1.37 ± 0.01∫
∣0.29 ± 0.01∣ ∣0.64 ± 0.01∣ ∣0.24 ± 0.01∣ ∣0.47 ± 0.01∣ ∣2.07 ± 0.16∣ ∣0.17 ± 0.01∣

Note. Values are means ± SD of three independent experiments. AM {FF}[OT] (MC) ∫EM∫ ∣PS∣. *Values significantly different (p < 0.05) from the control in each group.

Mahomoodally et al.

Mahomoodally et al. BMC Complementary and Alternative Medicine 2012 12:165   doi:10.1186/1472-6882-12-165

Open Data