GLY inhibits the release of MMP-2 and MMP-9 in VSMCs. (A). To examine the possible antimigration mechanisms of GLY, we determined the activity of MMP-2 and MMP-9 in culture media of VSMCs cells by zymographic analysis. (B). GLY inhibited MMP-9 and MMP-2 activities in a concentration-dependent manner. Values are means of three separate experiments, with standard errors represented by vertical bars. Mean value was significantly different from that of the control group :* p < 0.05,** p < 0.01, *** p < 0.001.
Chien et al. BMC Complementary and Alternative Medicine 2012 12:137 doi:10.1186/1472-6882-12-137