Table 2

Minimum Inhibitory concentrations of costunolide and eremanthin isolated from Costus speciosus against tested fungi using microdilution technique (μg/ml)

Tested organisms

Costunolide

Eremanthin

Fluconazole

Ketoconazole


Trichophyton mentagrophytes

62.5

125

25

< 12.5

Trichophyton simii

31.25

62.5

< 12.5

< 12.5

Trichophyton rubrum 296

31.25

62.5

< 12.5

< 12.5

Trichophyton rubrum 57

62.5

250

25

< 12.5

Epidermophyton floccosum

125

125

12.5

< 12.5

Scopulariopsis sp.

250

> 250

< 12.5

< 12.5

Aspergillus niger

250

125

100

< 12.5

Curvularia lunata

125

250

< 12.5

< 12.5

Magnaporthe grisea

250

250

nt

nt

Botrytis cinerea

> 250

> 250

nt

nt

Candida albicans

> 250

> 250

> 100

25


nt-not Tested

Fluconazole, Ketoconazole-standard antifungal agent

Costunolide, Eremanthin-Isolated compound

Duraipandiyan et al. BMC Complementary and Alternative Medicine 2012 12:13   doi:10.1186/1472-6882-12-13

Open Data