Change in skin epidermal thickness elicited by the repeated topical application of DNCB in NC/Nga mice. A) 8 μm-thick sections of DNCB-treated mice were fixed with formaldehyde and stained with hematoxylin and eosin; a. normal control, b. negative control (DNCB), c. positive control (DNCB + 1% pimecrolimus), d. 2% CDSW-treated (DNCB + 2% CDSW) e. 10% CDSW-treated (DNCB + 10% CDSW); (n = 10, magnification 200x, scale bars 200 μm). B) Epidermal thickness was measured by Micron (EVOS, v2.0) a digital imaging software (*p < 0.05).
Bak et al. BMC Complementary and Alternative Medicine 2012 12:108 doi:10.1186/1472-6882-12-108