Effect of different fractions of Oreocnide integrifolia on glucose stimulated insulin secretion. RINm5F cells were either cultured in basal (4.5 mM) or stimulated (16.7 mM) glucose concentrations in presence of fractions. Insulin secretion was quantified using Rat Insulin ELISA kit. Values are expressed as ± SEM in triplicates where • = p < 0.01, ■ = p < 0.001, ♦ = p < 0.0001: when control was compared with rest of the groups; α = p < 0.01, β = p < 0.01, δ = p < 0.01: when 4.5 mM glucose group was compared to rest of the groups and ➊ = p < 0.01, ➋ = p < 0.01, ➌ = p < 0.01: when 16.7 mM glucose group was compared to rest of the groups.
Ansarullah et al. BMC Complementary and Alternative Medicine 2011 11:126 doi:10.1186/1472-6882-11-126